What is chromium picolinate? Chromium picolinate is a mineral, an essential trace element for the human body. Chromium picolinate is an indispensable trace element for diabetics. Studies have shown that chromium picolinate has strong stability. As a fat-soluble non-electrolyte, it can smoothly pass through the cell membrane and directly act on tissue cells, enhance insulin activity, improve human glucose metabolism, and play an important role in the treatment of diabetes. It is suitable for diabetics and People with impaired glucose tolerance, high-risk diabetes and healthy people.